Procedure

Dexamethasone Suppression Test

8+experience
₹500consultation

Performed by Dr. Kavya Jonnalagadda at Sree Charith Hospital

The Dexamethasone Suppression Test helps diagnose conditions related to excess cortisol production, such as Cushing's syndrome. It involves taking a small dose of dexamethasone medication and measuring cortisol levels in blood or urine samples. Dr. Kavya Jonnalagadda performs this test at Sree Charith Hospital to evaluate adrenal and pituitary function.

Diagnostic blood test Outpatient procedure Hormone evaluation
1-3 days
Test Duration
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Dexamethasone Suppression Test at Sree Charith Hospital
At a Glance

Quick facts about this procedure.

Quick Facts
Procedure Duration1-3 days
Hospital StayOutpatient visits only
Return to WorkImmediate
Candidacy

Who is this procedure for?

This test may be recommended for people showing signs of excess cortisol, such as unexplained weight gain, high blood pressure, muscle weakness, or unusual skin changes.
It helps doctors determine whether hormone levels are normal or indicate a disorder like Cushing's syndrome.
Suitability for this test is decided after individual clinical assessment based on symptoms and medical history.
Transparency

What you should know before this procedure.

We believe in honest, upfront disclosure so you can make an informed decision.

Possible Risks

  • Allergic reaction to dexamethasone
  • Temporary blood sugar changes
  • Incorrect results if instructions not followed

Side Effects

  • Mild stomach upset
  • Temporary mood changes
  • Sleep disturbance
Procedure

How this procedure works.

A step-by-step look at what happens during this procedure.

1

Baseline measurement

A blood or urine sample is collected to measure your cortisol levels before taking any medication.

2

Dexamethasone dose

You take a prescribed dose of dexamethasone, usually at night. This medication normally suppresses cortisol production in healthy individuals.

3

Follow-up sample

Blood or urine is collected the next morning to see how your body responded to the medication.

4

Extended testing

In some cases, a longer test over two or three days with higher doses may be needed for more detailed information.

5

Results analysis

Your doctor compares cortisol levels before and after dexamethasone to determine if your adrenal glands and pituitary are functioning normally.

Timelines

Duration & timelines.

Initial consultation

Day 0

Baseline sample collection

Day 1 morning

Dexamethasone dose

Day 1 night

Follow-up sample

Day 2 morning

Extended testing (if needed)

Days 2-3

Results review

3-7 days after completion

Our Approach

How we handle this procedure.

A structured, patient-first approach from first consultation to full recovery.

Step 01

Initial consultation

Dr. Kavya Jonnalagadda reviews your symptoms, medical history, and any prior test results to determine if this test is appropriate for you.

Step 02

Clear instructions

You receive detailed written and verbal guidance on medication timing, what to avoid, and when to provide samples.

Step 03

Sample collection

Blood draws are performed by trained phlebotomists at Sree Charith Hospital with attention to comfort and accurate timing.

Step 04

Result interpretation

Results are explained in a follow-up consultation, along with recommended next steps based on your individual findings.

Recovery

Recovery & aftercare.

What to expect at each stage of your recovery journey.

ImmediateShort-termFollow-up

Immediate

Most people resume normal activities right after each blood draw. Any side effects from dexamethasone typically resolve within a day.

Short-term

If you experience temporary symptoms like mild stomach upset or sleep changes, these usually clear within 24 to 48 hours after the test is complete.

Follow-up

Your doctor will discuss results and any further testing or treatment needed based on your individual findings. Additional appointments depend on the diagnosis.

Outcomes

Treatment outcomes.

Accurate diagnosis

The test helps identify whether cortisol levels are elevated and where the problem originates, guiding appropriate treatment decisions.

Not a treatment

This is a diagnostic test only. It does not treat any underlying condition but provides information needed to plan therapy.

May require additional tests

Abnormal results often lead to imaging studies or additional hormone tests to pinpoint the exact cause of excess cortisol.

Normal results provide reassurance

If cortisol suppresses normally, it helps rule out certain hormone disorders and may redirect the search for other causes of symptoms.

Alternatives

Other options to consider.

The right choice depends on your diagnosis, risks and circumstances — discussed with you at your consultation.

24-hour urinary free cortisol

This test measures cortisol excreted in urine over a full day. It may be used instead of or alongside the suppression test to assess cortisol production.

Late-night salivary cortisol

Saliva samples collected at night can detect elevated cortisol. This option is less invasive and can be done at home, though it may not provide the same detail as suppression testing.

Direct imaging

In some cases, CT or MRI scans of the adrenal or pituitary glands are performed if there is strong clinical suspicion, though biochemical confirmation is usually needed first.

Myths vs Facts

Common misconceptions.

Let's clear up some of the most common myths about dexamethasone suppression test.

What happens if treatment is delayed?

  • If an underlying condition causing excess cortisol is not diagnosed and treated, it can lead to serious health problems over time. Uncontrolled cortisol elevation may worsen high blood pressure, diabetes, bone loss, and increase the risk of infections and heart disease. Early and accurate diagnosis through tests like this helps guide appropriate treatment to prevent these complications.
Related Conditions

Conditions we treat.

FAQ

About dexamethasone suppression test.

How accurate is the dexamethasone suppression test?
Can I eat and drink normally during the test?
Will dexamethasone cause side effects?
What happens if my results are abnormal?
How long does it take to get results?

Ready to take the first step?

Get a personalised assessment from an experienced specialist. Understand your options, ask your questions, and decide with confidence.

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